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The National Academy of Clinical Biochemistry is the Academy of the American Association for Clinical Chemistry (AACC) and is dedicated to advancing the science and practice of clinical laboratory medicine through research, education, and professional development. The Academy is a leading advocate for scholarship through scientific research and it conducts educational programs to promote scientific discovery, application, and integration. It publishes Laboratory Medicine Practice Guidelines (LMPG) for the application of clinical biochemistry to medical diagnosis and therapy.

Published Thyroid LMPG - Now Online!
Laboratory Support for the Diagnosis and Monitoring of Thyroid Disease

Published Hepatic Injury LMPG - Now Online!
Laboratory Guidelines for Screening, Diagnosis, and Monitoring of Hepatic Injury
Now available in word and PDF Formats

Published Cardiac LMPG - Now Online!
Recommendations For The Use Of Cardiac Markers In Coronary Artery Diseases
Now Available in Word and PDF Formats

Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold on the Internet
We can now use new methods to develop, validate and determine the identity, contents, and purity of samples of melanotan II peptide, a synthetic melanocortin receptor agonist, sold in vials as injectable skin-tanning products that were purchased from three online shops. Methods were based on liquid chromatography with ultra-violet detection (LC-UV) at wavelength 218 nm, and tandem mass spectrometric detection (MS/MS) after collision-induced fragmentation of the double charged [M+2H](2+) precursor ion (m/z 513). The Identification of melanotan II was verified by correct chromatographic retention time, and relative abundance ratios of 5 qualifying fragment ions. LC-UV was used to quantify melanotan II as well as impurities. Method validation was performed with reference to guidelines for assessing active substances in authorized medicinal products to reach acceptable accuracy and precision. Each shop claims vials contain 10 mg melanotan II. A broad range of peptide drugs used for enhancement purposes can be obtained from the illicit market. However, users of these drugs may be exposed to a range of potential harms, as shown in this study, given that these products are manufactured, distributed and supplied from an illicit market.